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COVID-19-Induced Myocarditis and mRNA Vaccine-Related Pericarditis: A Case Report. 2022

Clara L Voltarelli, and Luiza Silva, and Mariana Longo, and Stefany Ferraria, and Lucas L Martins, and Guilherme Nazar, and Tiago Magalhães, and Rafael Miyazima, and Gustavo Lenci Marques
Internal Medicine Department, Federal University of Parana, Curitiba, BRA.

Acute inflammatory cardiac disease is an increasing cause of COVID-19 vaccine-induced complications. We report a case of acute pericarditis following the second dose of the COVID-19 vaccine (BNT162b2) in a 49-year-old woman with previous COVID-19-induced myocarditis and heart failure. A clinical presentation compatible with acute decompensated heart failure elevated troponin levels and a cardiac-MRI showing myocardial fibrosis and inflammatory pericardial effusion led to the diagnosis of perimyocarditis. She was treated with non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine. Her condition improved in eight days. Physicians should be aware of the possible diagnosis of pericarditis and/or a myocardial injury after COVID-19 infection and vaccination.

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