BIOMAT Database Logo BIOMAT Database Logo

Assessing Trial-to-Trial Variability in Auditory ERPs in Autism and Schizophrenia. 2023

Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Department of Psychology and Center for Integrative Neuroscience, University of Nevada, Reno, Reno, NV, USA. shaigh@unr.edu.

Sensory abnormalities are characteristic of autism and schizophrenia. In autism, greater trial-to-trial variability (TTV) in sensory neural responses suggest that the system is more unstable. However, these findings have only been identified in the amplitude and not in the timing of neural responses, and have not been fully explored in schizophrenia. TTV in event-related potential amplitudes and inter-trial coherence (ITC) were assessed in the auditory mismatch negativity (MMN) in autism, schizophrenia, and controls. MMN was largest in autism and smallest in schizophrenia, and TTV was greater in autism and schizophrenia compared to controls. There were no differences in ITC. Greater TTV appears to be characteristic of both autism and schizophrenia, implicating several neural mechanisms that could underlie sensory instability.

UI MeSH Term Description Entries
D004569 Electroencephalography Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain. EEG,Electroencephalogram,Electroencephalograms
D005071 Evoked Potentials Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. Event Related Potential,Event-Related Potentials,Evoked Potential,N100 Evoked Potential,P50 Evoked Potential,N1 Wave,N100 Evoked Potentials,N2 Wave,N200 Evoked Potentials,N3 Wave,N300 Evoked Potentials,N4 Wave,N400 Evoked Potentials,P2 Wave,P200 Evoked Potentials,P50 Evoked Potentials,P50 Wave,P600 Evoked Potentials,Potentials, Event-Related,Event Related Potentials,Event-Related Potential,Evoked Potential, N100,Evoked Potential, N200,Evoked Potential, N300,Evoked Potential, N400,Evoked Potential, P200,Evoked Potential, P50,Evoked Potential, P600,Evoked Potentials, N100,Evoked Potentials, N200,Evoked Potentials, N300,Evoked Potentials, N400,Evoked Potentials, P200,Evoked Potentials, P50,Evoked Potentials, P600,N1 Waves,N2 Waves,N200 Evoked Potential,N3 Waves,N300 Evoked Potential,N4 Waves,N400 Evoked Potential,P2 Waves,P200 Evoked Potential,P50 Waves,P600 Evoked Potential,Potential, Event Related,Potential, Event-Related,Potential, Evoked,Potentials, Event Related,Potentials, Evoked,Potentials, N400 Evoked,Related Potential, Event,Related Potentials, Event,Wave, N1,Wave, N2,Wave, N3,Wave, N4,Wave, P2,Wave, P50,Waves, N1,Waves, N2,Waves, N3,Waves, N4,Waves, P2,Waves, P50
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000067877 Autism Spectrum Disorder Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V) Autistic Spectrum Disorder,Autism Spectrum Disorders,Autistic Spectrum Disorders,Disorder, Autistic Spectrum
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D001321 Autistic Disorder A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V) Autism, Infantile,Kanner's Syndrome,Autism,Autism, Early Infantile,Disorder, Autistic,Disorders, Autistic,Early Infantile Autism,Infantile Autism,Infantile Autism, Early,Kanner Syndrome,Kanners Syndrome
D012559 Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. Dementia Praecox,Schizophrenic Disorders,Disorder, Schizophrenic,Disorders, Schizophrenic,Schizophrenias,Schizophrenic Disorder

Related Publications

Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Auditory ERPs to non-target stimuli in schizophrenia: relationship to probability, task-demands, and target ERPs.
August 1994, International journal of psychophysiology : official journal of the International Organization of Psychophysiology,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Differential sensory fMRI signatures in autism and schizophrenia: Analysis of amplitude and trial-to-trial variability.
August 2016, Schizophrenia research,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Heart Rate Variability in Schizophrenia and Autism.
January 2021, Frontiers in psychiatry,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Auditory evoked potential variability in schizophrenia.
November 1970, Electroencephalography and clinical neurophysiology,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Trial-to-Trial Variability in Electrodermal Activity to Odor in Autism.
December 2020, Autism research : official journal of the International Society for Autism Research,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Auditory evoked potential variability in healthy and schizophrenia subjects.
August 2010, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Trial-to-trial variability and state-dependent modulation of auditory-evoked responses in cortex.
December 1999, The Journal of neuroscience : the official journal of the Society for Neuroscience,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Midlatency auditory event-related potentials in mice: comparison to midlatency auditory ERPs in humans.
September 2004, Brain research,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
Temporal variability of somatosensory, visual, and auditory evoked potentials in schizophrenia.
November 1979, Archives of general psychiatry,
Sarah M Haigh, and Laura Van Key, and Pat Brosseau, and Shaun M Eack, and David I Leitman, and Dean F Salisbury, and Marlene Behrmann
[Auditory P300 in assessing cognitive dysfunctions of Alzheimer's disease and schizophrenia].
June 1998, Zhonghua yi xue za zhi,
Copied contents to your clipboard!