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In 31 patients with congenital or acquired heart disease, functional class III NYHAC, effects of Sulfentanil (R 30730)--a new analgetic--on hemodynamics, inotropic state and myocardial oxygen consumption have been investigated intraoperatively, during extracorporeal circulation and postoperatively. Results are compared to a fentanyl-group and control-group. There was almost no change in cardiac index and stroke index. In comparison to fentanyl (dose relation fentanyl: sulfentanil = 10:1) there was a more pronounced decrease in aterial pressure, left ventricular pressure, peak dp/dt and myocardial oxygen consumption (-20%) in the sulfentanil-group. In contrast to the fentanyl-group there was, however, no increase in total pulmonary resistance with sulfentanil.
G Hempelmann, and
W Seitz, and
S Piepenbrock, and
E Schleussner
July 1977,
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G Hempelmann, and
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E Schleussner
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G Hempelmann, and
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E Schleussner
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G Hempelmann, and
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G Hempelmann, and
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Anesthesie, analgesie, reanimation,
