Paulo José Basso, and
Clarissa Ribeiro Reily Rocha, and
Erik A L Biessen, and
Ingrid Van der Pluijm, and
Carlos Frederico Martins Menck, and
Niels Olsen Saraiva Câmara
Laboratory of Immunobiology of Transplantation, Department of Immunology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.
UI
MeSH Term
Description
Entries
D007109
Immunity
Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances.
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.
DNA Injury,DNA Lesion,DNA Lesions,Genotoxic Stress,Stress, Genotoxic,Injury, DNA,DNA Injuries
D004260
DNA Repair
The removal of DNA LESIONS and/or restoration of intact DNA strands without BASE PAIR MISMATCHES, intrastrand or interstrand crosslinks, or discontinuities in the DNA sugar-phosphate backbones.
DNA Damage Response
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Ingrid Van der Pluijm, and
Carlos Frederico Martins Menck, and
Niels Olsen Saraiva Câmara
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Erik A L Biessen, and
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Carlos Frederico Martins Menck, and
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