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The immune response of young Nigerian children to a full course of infant immunizations was studied in relation to their nutritional state at the time of vaccination. No significant correlations were found between anthropometric measurements made at the time of vaccination and the antibody response to triple, polio, measles, meningococcal and typhoid vaccines. Significant correlations were found between serum pre-albumin levels and the response to group A meningococcal polysaccharide vaccine and between serum albumin levels and the response to group C meningococcal polysaccharide vaccine. These correlations may reflect the depressive effect of malaria both on serum albumin and pre-albumin levels and on immune responsiveness to meningococcal polysaccharides. No significant correlations were found between nutritional state at the time of BCG vaccination and the development of a positive tuberculin reaction five weeks later. We conclude that under-nutrition has little or no effect on the immune response to vaccines used in routine infant immunization programmes.
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
January 1996,
Bibliotheca nutritio et dieta,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
January 1986,
ASDC journal of dentistry for children,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
October 2005,
Journal of tropical pediatrics,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
March 2000,
Archivos latinoamericanos de nutricion,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
April 2005,
Fertility and sterility,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
May 1982,
The British journal of nutrition,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
February 1971,
Indian pediatrics,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
March 1987,
European journal of pediatrics,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
January 2019,
Skin pharmacology and physiology,
B M Greenwood, and
A M Bradley-Moore, and
A K Bradley, and
B R Kirkwood, and
H M Gilles
January 2009,
Journal of Ayub Medical College, Abbottabad : JAMC,
