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Ketoprofen, 50+50+100 mg, was compared to naproxen, 250+250+250 mg, in a double-blind, cross-over twice 4-weeks' study on patients with RA. There was no significant difference in the effect on morning stiffness, pain at rest, joint count, grip strength or ESR. Among 28 patients 10 preferred ketoprofen and 7 naproxen. Two ketoprofen and 1 naproxen periods were interrupted owing to intolerable side-effects. Twenty of the patients experienced some side-effect from at least one drug. The most common complaints were gastrointestinal, seen in 12 patients on ketoprofen and 9 on naproxen. Most side-effects were mild. No abnormality in blood morphology, liver function tests, serum creatinine or fasting blood glucose was observed. No occult bleeding was detected on routine stool examination.
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
January 1976,
Current medical research and opinion,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
November 1981,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
September 1985,
Clinical rheumatology,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
January 1977,
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F A Wollheim, and
Y Lindroth, and
K G Sjöblom
January 1980,
The Journal of rheumatology. Supplement,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
March 1978,
Archives of internal medicine,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
March 1984,
The British journal of clinical practice,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
January 1974,
Scandinavian journal of rheumatology,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
May 1982,
The New Zealand medical journal,
F A Wollheim, and
Y Lindroth, and
K G Sjöblom
December 1983,
Clinical rheumatology,
