[Prostacyclin--inhibitory effect on thrombocyte aggregation on the vascular wall in vivo?].
1978
H Sinzinger, and
K Silberbauer, and
M Winter
UI
MeSH Term
Description
Entries
D010974
Platelet Aggregation
The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.
Aggregation, Platelet
D011453
Prostaglandins
A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.
Prostaglandin,Prostanoid,Prostanoids
D011464
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).