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The response of murine lymphoreticular tissues to transplantation of a syngenic reticulosarcoma with mild transplantation antigenicity was studied by recording weight changes and histology. The results were compared with those obtained in normal mice and mice challenged with syngenic spleen cells. The tumor induced vigorous histological response in regional lymph nodes and mild response in nonregional lymph nodes and spleen. Mesenteric lymph nodes and thymus did not respond to the tumor. Observed morphological and gravimetrical changes indicated that both regional and nonregional lymph nodes and spleen take part in host immune response to tumor. A possible contamination of tumor tissue by viruses has been excluded.
Z P Pavelic, and
M Boranic, and
K Pavelic
June 1972,
European journal of cancer,
Z P Pavelic, and
M Boranic, and
K Pavelic
January 1982,
Czasopismo stomatologiczne,
Z P Pavelic, and
M Boranic, and
K Pavelic
October 1959,
Archivio per le scienze mediche,
Z P Pavelic, and
M Boranic, and
K Pavelic
June 1965,
British journal of cancer,
Z P Pavelic, and
M Boranic, and
K Pavelic
December 1978,
Zeitschrift fur Parasitenkunde (Berlin, Germany),
Z P Pavelic, and
M Boranic, and
K Pavelic
May 1978,
Immunology,
Z P Pavelic, and
M Boranic, and
K Pavelic
January 1966,
Giornale italiano di chirurgia,
Z P Pavelic, and
M Boranic, and
K Pavelic
January 1974,
Journal de gynecologie, obstetrique et biologie de la reproduction,
Z P Pavelic, and
M Boranic, and
K Pavelic
January 1957,
Ginekologia polska,
Z P Pavelic, and
M Boranic, and
K Pavelic
March 1955,
La Prensa medica mexicana,
