Relationship between Preoperative Nutritional Status and Clinical Outcomes in Patients with Head and Neck Cancer. 2022

En-Ying Wang, and Mu-Kuan Chen, and Ming-Yu Hsieh, and Chew-Teng Kor, and Yen-Tze Liu
Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.

The nutritional status in cancer patients is related to cancer survival and surgical outcome. The objective of this study was to examine the relationship between preoperative prognostic nutritional index (PNI) and post-operative clinical outcomes in head and neck cancer (HNC) patients. A total of 1282 head and neck cancer patients receiving surgical resection in Changhua Christian Hospital between 1 January 2010 and 30 August 2021 were recruited in the final analysis after undergoing propensity score matching analysis. The logistic regression model was used to assess the association of the PNI group with overall and various complications. The patients in the high PNI group had a significant lower incidence of overall complications, medical complications, and pulmonary complications; but not significant surgical complications. The high PNI group had lower mortality risk. The results in this study revealed that PNI score was a significant independent predictor of postoperative complications in HNC patients undergoing surgical resection. We recommend preoperative testing and evaluation of HNC patients to identify low PNI and high-risk groups for postoperative surveillance.

UI MeSH Term Description Entries
D009752 Nutritional Status State of the body in relation to the consumption and utilization of nutrients. Nutrition Status,Status, Nutrition,Status, Nutritional
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D006258 Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) Cancer of Head and Neck,Head Cancer,Head Neoplasm,Head and Neck Cancer,Head and Neck Neoplasm,Neck Cancer,Neck Neoplasm,Neck Neoplasms,Neoplasms, Upper Aerodigestive Tract,UADT Neoplasm,Upper Aerodigestive Tract Neoplasm,Upper Aerodigestive Tract Neoplasms,Cancer of Head,Cancer of Neck,Cancer of the Head,Cancer of the Head and Neck,Cancer of the Neck,Head Neoplasms,Head, Neck Neoplasms,Neoplasms, Head,Neoplasms, Head and Neck,Neoplasms, Neck,UADT Neoplasms,Cancer, Head,Cancer, Neck,Cancers, Head,Cancers, Neck,Head Cancers,Neck Cancers,Neoplasm, Head,Neoplasm, Neck,Neoplasm, UADT,Neoplasms, UADT
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D015596 Nutrition Assessment Evaluation and measurement of nutritional variables in order to assess the level of nutrition or the NUTRITIONAL STATUS of the individual. NUTRITION SURVEYS may be used in making the assessment. Prognostic Nutritional Index (PNI),Assessment, Nutrition,Mini Nutrition Assessment,Mini Nutritional Assessment,Nutrition Assessments,Nutrition Index,Nutrition Indexes,Nutrition Indices,Nutritional Assessment,Nutritional Index,Prognostic Nutritional Index,Assessment, Mini Nutrition,Assessment, Mini Nutritional,Assessment, Nutritional,Assessments, Mini Nutrition,Assessments, Mini Nutritional,Assessments, Nutrition,Assessments, Nutritional,Index, Nutrition,Index, Nutritional,Index, Prognostic Nutritional,Index, Prognostic Nutritional (PNI),Indexes, Nutrition,Indices, Nutrition,Indices, Nutritional,Indices, Prognostic Nutritional,Indices, Prognostic Nutritional (PNI),Mini Nutrition Assessments,Mini Nutritional Assessments,Nutrition Assessment, Mini,Nutrition Assessments, Mini,Nutritional Assessment, Mini,Nutritional Assessments,Nutritional Assessments, Mini,Nutritional Index, Prognostic,Nutritional Index, Prognostic (PNI),Nutritional Indices,Nutritional Indices, Prognostic,Nutritional Indices, Prognostic (PNI),Prognostic Nutritional Indices,Prognostic Nutritional Indices (PNI)

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