In gastric ulcer disease the operative procedure of choice is still partial gastrectomy, mostly carried out as Billroth I reconstruction with preservation of the duodenal passage. Indications for gastric resection are as follows: suspicion of malignancy, non-healing ulcers under conservative therapy, recurrent ulcer following conservative treatment, multiple and giant ulcers and ulcer complications like penetration, perforation, or bleeding. In duodenal ulcer gastric resection represents the exception. The routine operation is selective proximal vagotomy. The indication for partial gastrectomy in duodenal ulcer disease is: Recurrent ulcer after selective vagotomy (refractory to drugs), gastrin cell hyperplasia (hyper-function) and in rare cases of technical problems during surgery.