Modified-QuEChERS-LC/MS method for the analysis of aflatoxins and ochratoxin A in coriander seeds. 2023

Abdallah Ouakhssase, and Noureddine Fatini, and Elhabib Ait Addi
Equipe Génie des Procédés et Ingénierie Chimique (GPIC), Ecole Supérieure de Technologie d'Agadir, Université Ibn Zohr, Agadir, Morocco.

Coriander seeds consumption, like other spices, has increased due to its culinary use, medicinal benefits, and its essential oil. However, there are few reports in the scientific literature on the prevalence of mycotoxins in this spice. In this report, an easy and simple method was proposed for the determination of the aflatoxin group (AFB1, AFB2, AFG1, and AFG2) and ochratoxin A (OTA) in coriander seeds. The recoveries of analytes ranged from 72 to 102% in spiked samples (0.5-5 µg/kg), with RSD below 11%. The limits of quantification (LOQ) are between 0.12 and 0.5 µg/kg. The proposed method represents an improvement compared to previous studies. It was tested for the determination of 13 samples, proving that it is fast, efficient, and sensitive. Only OTA was identified in four samples, all at levels lower than the European limits defined for some spices (0.88 and 5.4 µg/kg). Such methods are needed for monitoring these toxins in this spice to ensure consumer safety and provide insight into their occurrence.

UI MeSH Term Description Entries
D009183 Mycotoxins Toxic compounds produced by FUNGI. Fungal Toxins,Mycotoxin,Toxins, Fungal
D009793 Ochratoxins Isocoumarins found in ASPERGILLUS OCHRACEUS and other FUNGI. Ochratoxin contaminated FOOD has been responsible for cases of FOODBORNE DISEASES. Ochratoxin
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D005506 Food Contamination The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage. Food Adulteration,Adulteration, Food,Adulterations, Food,Contamination, Food,Contaminations, Food,Food Adulterations,Food Contaminations
D000348 Aflatoxins Furano-furano-benzopyrans that are produced by ASPERGILLUS from STERIGMATOCYSTIN. They are structurally related to COUMARINS and easily oxidized to an epoxide form to become ALKYLATING AGENTS. Members of the group include AFLATOXIN B1; aflatoxin B2, aflatoxin G1, aflatoxin G2; AFLATOXIN M1; and aflatoxin M2. Aflatoxin
D012639 Seeds The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield. Diaspores,Elaiosomes,Embryos, Plant,Plant Embryos,Plant Zygotes,Zygotes, Plant,Diaspore,Elaiosome,Embryo, Plant,Plant Embryo,Plant Zygote,Seed,Zygote, Plant
D028526 Coriandrum A plant genus of the family APIACEAE. The leaves are the source of cilantro and the seeds are the source of coriander, both of which are used in SPICES. Cilantro,Coriander,Coriandrum sativum,Cilantros,Corianders,Coriandrum sativums,Coriandrums,sativums, Coriandrum

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