-transparent.png){kind=logo}
An immunoradiometric assay of thyroid stimulating hormone (TSH-IRMA) was evaluated as a first-line test for the diagnosis of thyroid disease in a prospective study of 318 consecutive patients in a major city hospital. The results of TSH-IRMA were compared with the diagnoses made by means of our usual diagnostic methods. Based on previous studies a serum TSH level of 0.15 mU/l was chosen as cutoff limit for calculation of diagnostic performance. For patients with serum TSH greater than 5.0 mU/l the results of TSH-IRMA were in accordance with the results of our routine radioimmunoassay. Patients with serum TSH levels between 0.15 mU/l and 5.0 mU/l were euthyroid (the diagnostic sensitivity was 100%). Consequently, the final diagnosis could be made with one test and within two days for 88% of patients. Patients with serum TSH less than 0.15 mU/l needed supplementary tests since only 32% of these patients had thyrotoxicosis, 32% had a non-toxic goiter, and 36% had no thyroid disease.
D Rønnov-Jessen, and
L Skov, and
J Faber
March 1987,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
D Rønnov-Jessen, and
L Skov, and
J Faber
May 1987,
Scandinavian journal of clinical and laboratory investigation,
D Rønnov-Jessen, and
L Skov, and
J Faber
January 1985,
British medical journal (Clinical research ed.),
D Rønnov-Jessen, and
L Skov, and
J Faber
January 1987,
Radioisotopes,
D Rønnov-Jessen, and
L Skov, and
J Faber
September 1984,
Radioisotopes,
D Rønnov-Jessen, and
L Skov, and
J Faber
November 1986,
Radioisotopes,
D Rønnov-Jessen, and
L Skov, and
J Faber
November 1984,
British medical journal (Clinical research ed.),
D Rønnov-Jessen, and
L Skov, and
J Faber
January 2002,
Papua and New Guinea medical journal,
D Rønnov-Jessen, and
L Skov, and
J Faber
April 1986,
Clinical chemistry,
D Rønnov-Jessen, and
L Skov, and
J Faber
February 1986,
Clinical endocrinology,
