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Intermittent Subcutaneous Injections of Apomorphine in Parkinson's Disease. 2022
Mustafa Ceylan, and
Murat Gültekin, and
Nazlı Durmaz Çelik, and
Bedia Samanci, and
Gül Yalçin Çakmakli, and
Rezzak Yilmaz
Department of Neurology, Atatürk University Faculty of Medicine, Movement Disorders and Neuromodulation Center, Erzurum, Turkey.
The intermittent subcutaneous injection of apomorphine is highly effective in the management of motor and non-motor symptoms of Parkinson's disease. Although it has been shown that apomorphine injection can be safely used in selected cases at all stages of the disease, there is no consensus regarding intermittent administration strategies. This review aimed to discuss the indications for intermittent subcutaneous apomorphine use in clinical practice, possible side effects and their management, and contraindicated cases in light of the literature and to present practical recommendations for clinical practice.
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