BIOMAT Database Logo BIOMAT Database Logo

Ciprofloxacin concentrations in human aqueous humor following intravenous administration. 1987

W Behrens-Baumann, and J Martell
Department of Ophthalmology, University of Göttingen, FRG.

16 patients received an intravenous infusion of 200 mg ciprofloxacin 1, 2, 3 and 6 h, respectively, before cataract extraction. This dosage produced mean aqueous humor levels of 0.165 +/- 0.09 and 0.126 +/- 0.028 microgram/ml after 1 and 3 h, respectively. The mean serum levels were 1.760 +/- 0.873 and 0.854 +/- 0.283 microgram/ml after 1 and 3 h, respectively. These levels are above the minimum inhibitory concentration of ciprofloxacin for sensitive organisms.

UI MeSH Term Description Entries
D007262 Infusions, Intravenous The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it. Drip Infusions,Intravenous Drip,Intravenous Infusions,Drip Infusion,Drip, Intravenous,Infusion, Drip,Infusion, Intravenous,Infusions, Drip,Intravenous Infusion
D008297 Male Males
D011292 Premedication Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION. Premedications
D002387 Cataract Extraction The removal of a cataractous CRYSTALLINE LENS from the eye. Enzymatic Zonulolysis,Phakectomy,Cataract Extractions,Enzymatic Zonulolyses,Extraction, Cataract,Extractions, Cataract,Phakectomies,Zonulolyses, Enzymatic,Zonulolysis, Enzymatic
D002939 Ciprofloxacin A broad-spectrum antimicrobial carboxyfluoroquinoline. Bay-09867,Ciprinol,Cipro,Ciprofloxacin Hydrochloride,Ciprofloxacin Hydrochloride Anhydrous,Ciprofloxacin Monohydrochloride Monohydrate,Anhydrous, Ciprofloxacin Hydrochloride,Bay 09867,Bay09867,Hydrochloride Anhydrous, Ciprofloxacin,Hydrochloride, Ciprofloxacin,Monohydrate, Ciprofloxacin Monohydrochloride,Monohydrochloride Monohydrate, Ciprofloxacin
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001082 Aqueous Humor The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319) Aqueous Flare,Intraocular Fluid,Aqueous Flares,Aqueous Humors,Flare, Aqueous,Fluid, Intraocular,Fluids, Intraocular,Humor, Aqueous,Humors, Aqueous,Intraocular Fluids

Related Publications

W Behrens-Baumann, and J Martell
Ceftizoxime concentrations in human aqueous humor following intravenous administration.
October 1988, Chemioterapia : international journal of the Mediterranean Society of Chemotherapy,
W Behrens-Baumann, and J Martell
Cefoperazone concentrations in human aqueous humor after intravenous administration.
July 1982, American journal of ophthalmology,
W Behrens-Baumann, and J Martell
Azlocillin concentrations in human aqueous humor after intravenous and subconjunctival administration.
January 1983, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
W Behrens-Baumann, and J Martell
Aqueous humor and plasma concentrations of ciprofloxacin and moxifloxacin following topical ocular administration in ophthalmologically normal horses.
May 2010, American journal of veterinary research,
W Behrens-Baumann, and J Martell
Fosfomycin levels in human aqueous humor after intravenous administration.
January 1985, Arzneimittel-Forschung,
W Behrens-Baumann, and J Martell
[Tobramycin concentration in human aqueous humor after intravenous administration].
November 1987, Nippon Ganka Gakkai zasshi,
W Behrens-Baumann, and J Martell
Moxalactam concentration in human aqueous humor after intravenous administration.
August 1982, Archives of ophthalmology (Chicago, Ill. : 1960),
W Behrens-Baumann, and J Martell
Concentrations of levofloxacin, ofloxacin, and ciprofloxacin in human corneal stromal tissue and aqueous humor after topical administration.
April 2004, Cornea,
W Behrens-Baumann, and J Martell
Ciprofloxacin and ofloxacin aqueous humor concentrations after topical administration in dogs undergoing cataract surgery.
January 2005, Veterinary ophthalmology,
W Behrens-Baumann, and J Martell
Lung tissue concentrations of ciprofloxacin following intravenous administration in patients.
May 1989, Arzneimittel-Forschung,
Copied contents to your clipboard!