Although a large number of studies have examined the relationship between the Big Five personality traits and driving behaviors, consistent evidence for their relationships is still lacking. The main purpose of this study was to systematically review the relationships between the Big Five personality traits and various driving behaviors with different intentions (including risky, aggressive, and positive driving behaviors) through a meta-analysis. A total of 34 articles met the inclusion criteria for the meta-analysis. The results showed that risky and aggressive driving behaviors were negatively associated with conscientiousness (r = -0.21; r = -0.26), agreeableness (r = -0.23; r = -0.37), and openness (r = -0.08; r = -0.07), positively associated with neuroticism (r = 0.11; r = 0.26), and nonsignificantly associated with extraversion (r = 0.06; r = -0.06). Positive driving behaviors were positively associated with conscientiousness (r = 0.30), agreeableness (r = 0.32) and openness (r = 0.20) but nonsignificantly associated with extraversion (r = 0.08) and neuroticism (r = -0.10). In addition, the association between the Big Five personality traits and driving behaviors could be moderated by age, gender and type of personality measure. In conclusion, this study contributes to the literature by quantitatively synthesizing existing findings and reconciling previous debates on the relationship between the Big Five personality traits and driving behaviors. From a practical perspective, our findings provide valuable insights into driver selection and screening, policy development, and safety intervention design.