Isolation and characterization of an alphoid DNA sequence recently amplified on human chromosome 3.
1987
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
Génétique des Tumeurs, Institut Curie, Paris, France.
UI
MeSH Term
Description
Entries
D002893
Chromosomes, Human, Pair 3
A specific pair of human chromosomes in group A (CHROMOSOMES, HUMAN, 1-3) of the human chromosome classification.
Chromosome 3
D003001
Cloning, Molecular
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Molecular Cloning
D004247
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D005784
Gene Amplification
A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.
Amplification, Gene
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
Related Publications
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
O Delattre, and
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E Viegas-Pequignot, and
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N Van Cong, and
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F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
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N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
August 1990,
Japanese journal of cancer research : Gann,
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
January 1987,
The International journal of biochemistry,
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux
O Delattre, and
A Bernard, and
B Malfoy, and
F Marlhens, and
E Viegas-Pequignot, and
C Brossard, and
O Haguenauer, and
N Creau-Goldberg, and
N Van Cong, and
B Dutrillaux