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Using 123I-omega-heptadecanoic acid (HDA) and 201Tl, respectively, myocardial fatty acid metabolism and perfusion were studied in 51 symptomatic patients with mitral valve prolapse (MVP) as diagnosed by ventriculography, and no evidence of coronary artery disease. Twelve subjects with normal coronary arteries and normal ventriculogram served as a control group for the evaluation of elimination kinetics of HDA. In the control group, the mean elimination half-life was 26.1 +/- 3.6 min, whereas the patients with MVP had a mean value of 25.0 +/- 6.4 min. In patients with MVP, a high incidence concerning abnormalities of accumulation and/or elimination of HDA occurred, namely accumulation defects in 31% and both prolonged and shortened elimination half-lives in 16% and 29%, respectively. Myocardial perfusion scintigraphy using 201Tl showed abnormalities in 76%. Correlations were found between decreased uptake of HDA and prolonged elimination half-life as well as defects by 201Tl, presumably due to ischemia based on small-vessel disease or abnormalities of cellular metabolism.
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 1980,
Chest,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
September 1977,
British heart journal,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 2010,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
September 1978,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 1986,
European journal of nuclear medicine,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 1976,
The American journal of cardiology,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 1988,
Radiologia diagnostica,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
June 1981,
Arquivos brasileiros de cardiologia,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
September 2009,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
E Voth, and
H Schicha, and
U Tebbe, and
P Neumann, and
D Emrich
January 1977,
British heart journal,
