-transparent.png){kind=logo}
Forty male guinea-pigs weighing 400-600 g, 8 months old, were given metribuzin directly into the gastric lumen over a period of 30 days (20 animals) or 90 days (20 animals), 6 times a week. The intoxicated animals showed congestion and obliteration of the trabecular structure of the liver. Acidophilic and vacuolar degeneration of the liver cells with signs of necrosis were also observed. Histochemical tests revealed a poorer staining for glycogen and succinic dehydrogenase and intensification of the alkaline and acid phosphatases reaction. The above findings indicate a progressive degeneration due to metribuzin of different organelles of the liver cells including nuclei, mitochondria, lysosomes, microvilli and the cytoplasm.
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
March 1948,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
January 1974,
Acta biologica Academiae Scientiarum Hungaricae,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
January 1978,
Acta oto-laryngologica,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
March 1974,
L'union medicale du Canada,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
April 1948,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
August 1977,
Archives of oto-rhino-laryngology,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
January 1967,
Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
January 1967,
Folia morphologica,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
December 1952,
Okajimas folia anatomica Japonica,
J Tomaszewski, and
K Zwierz, and
B Musiatowicz, and
C Jezyna
October 1961,
Journal of anatomy,
