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Parotid ducts were ligated unilaterally in rats for periods from 6 h to 5 months. A slight increase in gland weight was observed during the first 24 h; thereafter, the weight gradually fell, being less than 50% of controls at 5 months. The activity of the putrescine-forming enzyme, ornithine decarboxylase (ODC), increased with peak values by 3 days and 3 weeks. However, the putrescine content had already reached its highest value by 24 h. A notably marked reduction of spermidine and spermine contents was observed by 1 day after ligation and throughout the whole time of observation. The results suggest that an inverse polyamine metabolism occurred, that is, spermine converts to spermidine which in turn converts to putrescine.
B O Nilsson, and
J Ekström, and
E Rosengren
December 1962,
Archives of surgery (Chicago, Ill. : 1960),
B O Nilsson, and
J Ekström, and
E Rosengren
January 2012,
Advances in oto-rhino-laryngology,
B O Nilsson, and
J Ekström, and
E Rosengren
January 1975,
Stomatologiia,
B O Nilsson, and
J Ekström, and
E Rosengren
January 1982,
Archives of oral biology,
B O Nilsson, and
J Ekström, and
E Rosengren
March 1973,
Virchows Archiv. A, Pathology. Pathologische Anatomie,
B O Nilsson, and
J Ekström, and
E Rosengren
April 2014,
Biotechnic & histochemistry : official publication of the Biological Stain Commission,
B O Nilsson, and
J Ekström, and
E Rosengren
January 2024,
JAMA otolaryngology-- head & neck surgery,
B O Nilsson, and
J Ekström, and
E Rosengren
October 2002,
The Histochemical journal,
B O Nilsson, and
J Ekström, and
E Rosengren
January 1974,
Journal of oral pathology,
B O Nilsson, and
J Ekström, and
E Rosengren
July 1979,
Plastic and reconstructive surgery,
