Pigmented Basal Cell Carcinoma: An Argument for Sub-Classification. 2023

Autumn Saizan, and Susan Taylor, and Nada Elbuluk

Basal cell carcinoma (BCC) has several subclassifications, including pigmented basal cell carcinoma. In our clinical experience, we have found that pigmented basal cell carcinoma itself has multiple subtypes which can overlap with traditional basal cell carcinoma subclassifications. In this letter, we argue for the subclassification of pigmented basal cell carcinoma, as either superficial, nodular, or morpheaform. We believe further subclassification of pigmented BCCs may reveal important therapeutic and prognostic differences which could make an impact on the morbidity and mortality of this condition for those affected, many of whom are skin of color patients that are already disproportionately affected by health disparities related to skin cancer. J Drugs Dermatol. 2023;22(2): 217-218. doi:10.36849/JDD.6883.

UI MeSH Term Description Entries
D002280 Carcinoma, Basal Cell A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471) Carcinoma, Basal Cell, Pigmented,Epithelioma, Basal Cell,Rodent Ulcer,Ulcer, Rodent,Basal Cell Carcinoma,Basal Cell Carcinomas,Basal Cell Epithelioma,Basal Cell Epitheliomas,Carcinomas, Basal Cell,Epitheliomas, Basal Cell,Rodent Ulcers,Ulcers, Rodent
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm

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