[Infiltrating cancer of the bladder with lymph node invasion: is total cystectomy justified?]. 1987

M Zerbib, and L Boccon-Gibod, and A Steg
Clinique Urologique, Hôpital Cochin, Paris.

In order to assess the potential benefits of radical cystectomy in bladder cancer associated with pelvic lymph node metastasis, a retrospective study compared 2 groups of patients with T2-T3 N+ bladder cancer: 10 treated by radical cystectomy and 14 treated conservatively once the diagnosis of nodal metastasis had been established by fine needle node aspiration or lymphadenectomy. The survival rates were identical in both groups: 80% of the patients died within 2 years, 60% during the first year after diagnosis, mainly due to distant metastasis. No patient in the conservative arm required salvage cystectomy because of local progression. It is concluded that radical cystectomy is of little benefit in T2-T3 N+ bladder cancer, a disease which is no longer amenable to purely local treatment.

UI MeSH Term Description Entries
D008207 Lymphatic Metastasis Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. Lymph Node Metastasis,Lymph Node Metastases,Lymphatic Metastases,Metastasis, Lymph Node
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001749 Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER. Bladder Cancer,Bladder Neoplasms,Cancer of Bladder,Bladder Tumors,Cancer of the Bladder,Malignant Tumor of Urinary Bladder,Neoplasms, Bladder,Urinary Bladder Cancer,Bladder Cancers,Bladder Neoplasm,Bladder Tumor,Cancer, Bladder,Cancer, Urinary Bladder,Neoplasm, Bladder,Neoplasm, Urinary Bladder,Tumor, Bladder,Tumors, Bladder,Urinary Bladder Neoplasm
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

Related Publications

M Zerbib, and L Boccon-Gibod, and A Steg
January 1989, Progress in clinical and biological research,
M Zerbib, and L Boccon-Gibod, and A Steg
January 2002, International braz j urol : official journal of the Brazilian Society of Urology,
M Zerbib, and L Boccon-Gibod, and A Steg
January 1985, Journal d'urologie,
M Zerbib, and L Boccon-Gibod, and A Steg
April 1947, The Journal of urology,
M Zerbib, and L Boccon-Gibod, and A Steg
June 1979, Journal d'urologie et de nephrologie,
M Zerbib, and L Boccon-Gibod, and A Steg
September 2002, Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie,
M Zerbib, and L Boccon-Gibod, and A Steg
January 2020, Journal of cellular biochemistry,
M Zerbib, and L Boccon-Gibod, and A Steg
July 2019, Pathology oncology research : POR,
Copied contents to your clipboard!