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Behaviour of modified nucleosides, tRNA components, and their analogues has been studied in the internucleotide bond formation catalysed by ribonucleases of various substrate specificity, polynucleotide phosphorylases, and T4 RNA ligase and the results are summarised in this paper. Pseudouridine, dihydrouridine, ribothymidine, 5-methylcytidine, inosine, and 6-methyladenosine can participate in the reaction of internucleotide bond formation the presence of most ribonucleases used, viz. Pb2, Pcl2, Pb1, Pch1, C2, T1, pancreatic RNase. 3-Methylcytidine and 4-acetylcytidine form internucleotide bond (as phosphate acceptors) usually by means of guanyl-specific ribonucleases, whereas 1-methylandenosine is incorporated with ribonuclease Pel2. 7-Methylguanosine and 1-methylguynosine 2',3'-cyclophosphates can be used as phosphate donors in the presence of ribonuclease Pb2; in the similar enzymatic reaction 6-isopentenyladenosine is an uneffective acceptor.
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
January 2007,
Nucleosides, nucleotides & nucleic acids,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
January 1994,
Methods in molecular biology (Clifton, N.J.),
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
January 1991,
Nucleic acids symposium series,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
January 2002,
Nucleic acids research. Supplement (2001),
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
March 2004,
Bioorganic & medicinal chemistry,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
September 2005,
The Journal of organic chemistry,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
January 2006,
Nucleic acids symposium series (2004),
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
March 2020,
Current protocols in nucleic acid chemistry,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
November 1998,
Nucleic acids research,
S M Zhenodarova, and
V P Kliagina, and
E A Sedel'nikova, and
O A Smolianinova, and
I A Soboleva
September 1992,
Nucleic acids research,
