Erythropoiesis and anaemia in heterozygous beta-thalassaemia.
1987
P Fessas, and
T Tassiopoulos
UI
MeSH Term
Description
Entries
D004920
Erythropoiesis
The production of red blood cells (ERYTHROCYTES). In humans, erythrocytes are produced by the YOLK SAC in the first trimester; by the liver in the second trimester; by the BONE MARROW in the third trimester and after birth. In normal individuals, the erythrocyte count in the peripheral blood remains relatively constant implying a balance between the rate of erythrocyte production and rate of destruction.
Erythropoieses
D006579
Heterozygote
An individual having different alleles at one or more loci regarding a specific character.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000740
Anemia
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
Anemias
D013789
Thalassemia
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.