BIOMAT Database Logo BIOMAT Database Logo

Analysis of sex and regional differences in androgen receptors in fetal rhesus monkey brain. 1987

S M Pomerantz, and S A Sholl
Department of Physiology, University of Pittsburgh, PA 15261.

Cytosolic androgen receptor levels were measured in different brain regions of fetal male and female rhesus monkeys (day 135 post-conception). The hypothalamus-preoptic area, amygdala and cerebellum exhibited higher receptor concentration in comparison to the cerebral cortex (parietal, temporal frontal, and occipital lobes), hippocampus and cingulate gyrus (P less than 0.001). No sexual difference in receptor concentrations was found except in the amygdala where fetal males exhibited slightly higher levels than females. The similarity in androgen receptor levels suggests that the developing brain of both sexes could be influenced by circulating androgens under normal or pathological conditions.

UI MeSH Term Description Entries
D008251 Macaca A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes. Ape, Barbary,Ape, Black,Ape, Celebes,Barbary Ape,Black Ape,Celebes Ape,Macaque,Apes, Barbary,Apes, Black,Apes, Celebes,Barbary Apes,Black Apes,Celebes Apes,Macacas,Macaques
D008253 Macaca mulatta A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans. Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D008297 Male Males
D011944 Receptors, Androgen Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA. Androgen Receptors,5 alpha-Dihydrotestosterone Receptor,Androgen Receptor,Dihydrotestosterone Receptors,Receptor, Testosterone,Receptors, Androgens,Receptors, Dihydrotestosterone,Receptors, Stanolone,Stanolone Receptor,Testosterone Receptor,5 alpha Dihydrotestosterone Receptor,Androgens Receptors,Receptor, 5 alpha-Dihydrotestosterone,Receptor, Androgen,Receptor, Stanolone,Stanolone Receptors,alpha-Dihydrotestosterone Receptor, 5
D001923 Brain Chemistry Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states. Chemistry, Brain,Brain Chemistries,Chemistries, Brain
D005260 Female Females
D005333 Fetus The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN. Fetal Structures,Fetal Tissue,Fetuses,Mummified Fetus,Retained Fetus,Fetal Structure,Fetal Tissues,Fetus, Mummified,Fetus, Retained,Structure, Fetal,Structures, Fetal,Tissue, Fetal,Tissues, Fetal
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012733 Sex Differentiation The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain. Differentiation, Sex,Sexual Differentiation,Differentiation, Sexual
D013196 Dihydrotestosterone A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. 5 alpha-Dihydrotestosterone,Androstanolone,Stanolone,17 beta-Hydroxy-5 beta-Androstan-3-One,17beta-Hydroxy-5alpha-Androstan-3-One,5 beta-Dihydrotestosterone,5-alpha Dihydrotestosterone,5-alpha-DHT,Anaprotin,Andractim,Dihydroepitestosterone,Gelovit,17 beta Hydroxy 5 beta Androstan 3 One,17beta Hydroxy 5alpha Androstan 3 One,5 alpha DHT,5 alpha Dihydrotestosterone,5 beta Dihydrotestosterone,Dihydrotestosterone, 5-alpha,beta-Hydroxy-5 beta-Androstan-3-One, 17

Related Publications

S M Pomerantz, and S A Sholl
Effects of exogenous androgen on brain androgen receptors of the fetal rhesus monkey.
March 1994, Neuroendocrinology,
S M Pomerantz, and S A Sholl
Ontogeny of cytosolic androgen receptors in the brain of the fetal rhesus monkey.
May 1988, Endocrinology,
S M Pomerantz, and S A Sholl
Estrogen receptors in the rhesus monkey brain during fetal development.
December 1989, Brain research. Developmental brain research,
S M Pomerantz, and S A Sholl
Sex differences in estrogen and androgen receptors in hamster brain.
January 1992, Life sciences,
S M Pomerantz, and S A Sholl
Androgen receptors in the prostate of the Rhesus monkey.
January 1977, Urological research,
S M Pomerantz, and S A Sholl
Androgen secretion by the fetal and neonatal rhesus monkey.
October 1970, Endocrinology,
S M Pomerantz, and S A Sholl
Androgen receptors from the epididymis of the rhesus monkey.
January 1974, Endocrine research communications,
S M Pomerantz, and S A Sholl
Androgen receptors are differentially distributed between right and left cerebral hemispheres of the fetal male rhesus monkey.
May 1990, Brain research,
S M Pomerantz, and S A Sholl
Sex differences in adolescent rhesus monkey (Macaca mulatta) Behavior.
January 1993, American journal of primatology,
S M Pomerantz, and S A Sholl
Analysis of Rhesus monkey vocalizations: maturation-related sex differences in clear-cell frequency.
March 1973, American journal of physical anthropology,
Copied contents to your clipboard!