-transparent.png){kind=logo}
The potential for certain constituents in intraocular lenses, such as monomer methylmethacrylate (MMM), to induce toxic effects after intraocular implantation not only depends on their toxic potency, but also on the characteristics of their release, accumulation, and elimination from the aqueous humor. A mathematical estimation taking these factors into account shows that for a lens mass of approximately 15 mg, the concentration of MMM in the aqueous humor amounts to about 10(-4) of the respective concentration in the lens, but that value is maintained for several weeks. Therefore, experiments to test the chemical toxicity of MMM or similar lens compounds in eyes must not only take into account the actual concentration limit but also the time of exposure to the substance.
K Ludwig, and
O F Scheiffarth, and
O E Lund
February 2006,
Journal of cataract and refractive surgery,
K Ludwig, and
O F Scheiffarth, and
O E Lund
January 1982,
Archives of ophthalmology (Chicago, Ill. : 1960),
K Ludwig, and
O F Scheiffarth, and
O E Lund
December 1997,
Yan ke xue bao = Eye science,
K Ludwig, and
O F Scheiffarth, and
O E Lund
January 1980,
Archives of ophthalmology (Chicago, Ill. : 1960),
K Ludwig, and
O F Scheiffarth, and
O E Lund
June 2009,
Journal of cataract and refractive surgery,
K Ludwig, and
O F Scheiffarth, and
O E Lund
January 1989,
Refractive & corneal surgery,
K Ludwig, and
O F Scheiffarth, and
O E Lund
January 1999,
Klinika oczna,
K Ludwig, and
O F Scheiffarth, and
O E Lund
August 2001,
Cornea,
K Ludwig, and
O F Scheiffarth, and
O E Lund
October 1986,
Acta ophthalmologica,
K Ludwig, and
O F Scheiffarth, and
O E Lund
January 1983,
American journal of ophthalmology,
