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Idiopathic partial central diabetes insipidus. 2023

Larissa Fabre, and Viviane Calice da Silva
Hospital Regional Hans Dieter Schmidt, Joinville, SC, Brazil.

Diabetes insipidus is a rare disorder characterized by the inability to concentrate urine, which results in hypotonic urine and increased urinary volume. It may occur because of antidiuretic hormone deficiency or resistance to its action in the renal tubules. When there is a deficiency in the synthesis of antidiuretic hormones, diabetes insipidus is called central; when there is resistance to its action in the renal tubules, it is said to be nephrogenic. We report a case of idiopathic partial central diabetes insipidus and highlight the management and treatment of the disease.

UI MeSH Term Description Entries
D003919 Diabetes Insipidus A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
D003920 Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D020790 Diabetes Insipidus, Neurogenic A genetic or acquired polyuric disorder caused by a deficiency of VASOPRESSINS secreted by the NEUROHYPOPHYSIS. Clinical signs include the excretion of large volumes of dilute URINE; HYPERNATREMIA; THIRST; and polydipsia. Etiologies include HEAD TRAUMA; surgeries and diseases involving the HYPOTHALAMUS and the PITUITARY GLAND. This disorder may also be caused by mutations of genes such as ARVP encoding vasopressin and its corresponding neurophysin (NEUROPHYSINS). Central Diabetes Insipidus,Diabetes Insipidus Cranial Type,Diabetes Insipidus Primary Central,Diabetes Insipidus Secondary To Vasopressin Deficiency,Diabetes Insipidus, Central,Diabetes Insipidus, Cranial Type,Diabetes Insipidus, Neurohypophyseal,Diabetes Insipidus, Neurohypophyseal Type,Diabetes Insipidus, Pituitary,Diabetes Insipidus, Primary Central,Neurogenic Diabetes Insipidus,Neurohypophyseal Diabetes Insipidus,Pituitary Diabetes Insipidus,Vasopressin Defective Diabetes Insipidus,Vasopressin Deficiency

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