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Acute pancreatitis was diagnosed in 2 dogs given azathioprine and prednisone. Prednisone and azathioprine had been given as immunosuppressive therapy for pemphigus foliaceus in dog 1 and for polymyositis in dog 2. Azathioprine was discontinued in both dogs. In dog 1, prednisone was reinstituted on day 6 of hospitalization. Prednisone was continued throughout the period of hospitalization in dog 2. Both dogs recovered without complication. Glucocorticoid therapy has been associated with the development of pancreatitis. In human beings, a common side effect of azathioprine is the development of drug-induced pancreatitis. Definitive identification of azathioprine as the cause of pancreatitis in these dogs was not possible; the owners refused to permit retreatment with the drug. Therefore, the synergistic action between these 2 drugs could not be ruled out as the cause of pancreatitis.
K A Moriello, and
D Bowen, and
D J Meyer
August 1991,
The Canadian veterinary journal = La revue veterinaire canadienne,
K A Moriello, and
D Bowen, and
D J Meyer
August 1973,
The New England journal of medicine,
K A Moriello, and
D Bowen, and
D J Meyer
September 1977,
The American journal of digestive diseases,
K A Moriello, and
D Bowen, and
D J Meyer
October 1990,
Annales de gastroenterologie et d'hepatologie,
K A Moriello, and
D Bowen, and
D J Meyer
December 1972,
Transplantation proceedings,
K A Moriello, and
D Bowen, and
D J Meyer
August 1990,
Transplantation,
K A Moriello, and
D Bowen, and
D J Meyer
July 1980,
Annals of internal medicine,
K A Moriello, and
D Bowen, and
D J Meyer
March 2019,
The Lancet. Child & adolescent health,
K A Moriello, and
D Bowen, and
D J Meyer
September 1974,
Modern veterinary practice,
K A Moriello, and
D Bowen, and
D J Meyer
April 2012,
QJM : monthly journal of the Association of Physicians,
