Biomaterial Database

Effect of malathion on some kinesiological parameters of the gastrocnemius muscle of frog, Rana hexadactyla (Lesson) and the antagonistic action of atropine. 1987

T Kowsalya, and K S Rao, and K V Rao

Zoology Department, S.V. University P.G. Center, Kavali, India.

Selected kinesiological parameters were studied in the gastrocnemius muscle of frog, R. hexadactyla Lesson, under different treatments with malathion and atropine. There is an apparent decrease of twitch amplitude, half contraction time, half relaxation time, twitch duration and fatigue time in control muscle during malathion treatment. In the denervated muscle, twitch amplitude, latency period, and fatigue time were lowered, with elevated phases of contraction and relaxation time. However, all these parameters except fatigue time showed an elevatory trend when atropine was given along with malathion revealing its antagonistic action against malathion toxicity. All these results indicate that the action of malathion is similar to that of a pharmacologically active myo- and neurotoxic agent.

UI	MeSH Term	Description	Entries
D008294	Malathion	A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.	Carbafos,Carbofos,Carbophos,Cythion,Karbofos,Prioderm,Sadophos
D009119	Muscle Contraction	A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D011898	Ranidae	The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica.	Frogs, True,Rana,Frog, True,True Frog,True Frogs
D011930	Reaction Time	The time from the onset of a stimulus until a response is observed.	Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D003714	Denervation	The resection or removal of the nerve to an organ or part.	Laser Neurectomy,Neurectomy,Peripheral Neurectomy,Radiofrequency Neurotomy,Denervations,Laser Neurectomies,Neurectomies,Neurectomies, Laser,Neurectomies, Peripheral,Neurectomy, Laser,Neurectomy, Peripheral,Neurotomies, Radiofrequency,Neurotomy, Radiofrequency,Peripheral Neurectomies,Radiofrequency Neurotomies
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001285	Atropine	An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.	AtroPen,Atropin Augenöl,Atropine Sulfate,Atropine Sulfate Anhydrous,Atropinol,Anhydrous, Atropine Sulfate,Augenöl, Atropin,Sulfate Anhydrous, Atropine,Sulfate, Atropine