-transparent.png){kind=logo}
The arrangement of the disulphide bridges in human low-Mr kininogen has been elucidated. Low-Mr kininogen contains 18 half-cystine residues forming nine disulphide bridges. The first and the last half-cystine residues of the amino acid sequence form a disulphide loop which spans the heavy- and the light-chain portion of the kininogen molecule. The other 16 half-cystine residues are linked consecutively to form eight loops of 4-20 amino acids; these loops are lined up in the heavy-chain portion of the kininogen molecule. In this way, a particular pattern of disulphide loops is formed which seems to be of critical importance for the inhibitor function of human kininogen.
Related Publications
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
May 1969,
Biochimica et biophysica acta,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
November 1994,
The Journal of dairy research,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
June 1954,
The Biochemical journal,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
July 1965,
Journal of molecular biology,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
August 1968,
FEBS letters,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
December 1967,
Nature,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
January 1971,
The Biochemical journal,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
October 1966,
The Biochemical journal,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
September 1981,
Journal of molecular biology,
J Kellermann, and
C Thelen, and
F Lottspeich, and
A Henschen, and
R Vogel, and
W Müller-Esterl
July 1965,
Journal of molecular biology,
