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Upon exposure to a specific antigen, granulation of basophils bearing IgE disappears. The aim of this study was to assess the human basophil degranulation (HBD) test with hydatic antigen in 100 patients. Seventy patients were clinically suspected of having liver hydatidosis (LH) (group I). Eight patients had asymptomatic hepatic calcifications. Twenty-two patients had previous surgery for LH (group III). In group I the percentage of HBD was significantly higher in patients with LH (23 of 70) than in patients with other hepatobiliary diseases (P less than 0.001). In group II all patients had negative HBD tests. In group III the test became negative within 8-12 months after radical surgery in four patients, and remained positive in the other 18. These results suggest that the HBD test is useful for the diagnosis of LH. In asymptomatic patients with hepatic calcified cyst, a negative HBD test suggests a dead parasite. In previously operated patients, a positive test suggests persistence of antigen.
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
June 1983,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
June 1987,
Journal of the Egyptian Society of Parasitology,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
January 1986,
Allergologia et immunopathologia,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
February 1983,
Nihon Jibiinkoka Gakkai kaiho,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
January 1981,
La Nouvelle presse medicale,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
September 1980,
Annales de la Societe belge de medecine tropicale,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
March 1981,
Bulletin des societes d'ophtalmologie de France,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
June 1967,
Annals of allergy,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
June 1966,
Lijecnicki vjesnik,
M Huguier, and
F Leynadier, and
S Houry, and
F Lacaine, and
J Dry
June 1983,
Presse medicale (Paris, France : 1983),
