| D010300 |
Parkinson Disease |
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary |
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| D004421 |
Dystonia |
An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77) |
Muscle Dystonia,Dystonia, Diurnal,Dystonia, Limb,Dystonia, Paroxysmal,Diurnal Dystonia,Dystonia, Muscle,Limb Dystonia,Paroxysmal Dystonia |
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| D005246 |
Feedback |
A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system. |
Feedbacks |
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| D005917 |
Globus Pallidus |
The representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. It forms the smaller, more medial part of the lentiform nucleus. |
Paleostriatum,Pallidum,Pallidums |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D046690 |
Deep Brain Stimulation |
Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously. |
Brain Stimulation, Deep,Electrical Stimulation of the Brain,Brain Stimulations, Deep,Deep Brain Stimulations,Stimulation, Deep Brain,Stimulations, Deep Brain |
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| D020821 |
Dystonic Disorders |
Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset. |
Familial Dystonia,Focal Dystonia,Pseudodystonia,Writer's Cramp,Adult-Onset Dystonias,Adult-Onset Idiopathic Focal Dystonias,Adult-Onset Idiopathic Torsion Dystonias,Autosomal Dominant Familial Dystonia,Autosomal Recessive Familial Dystonia,Childhood Onset Dystonias,Dystonia Disorders,Dystonia, Hereditary,Dystonia, Primary,Dystonia, Psychogenic,Dystonia, Secondary,Dystonias, Sporadic,Familial Dystonia, Autosomal Dominant,Familial Dystonia, Autosomal Recessive,Familial Dystonia, Idiopathic,Secondary Dystonia,Adult Onset Dystonias,Adult Onset Idiopathic Focal Dystonias,Adult Onset Idiopathic Torsion Dystonias,Adult-Onset Dystonia,Childhood Onset Dystonia,Dystonia Disorder,Dystonia, Adult-Onset,Dystonia, Childhood Onset,Dystonia, Familial,Dystonia, Focal,Dystonia, Idiopathic Familial,Dystonia, Sporadic,Dystonias, Adult-Onset,Dystonias, Childhood Onset,Dystonias, Familial,Dystonias, Focal,Dystonias, Hereditary,Dystonias, Idiopathic Familial,Dystonias, Primary,Dystonias, Psychogenic,Dystonias, Secondary,Dystonic Disorder,Familial Dystonias,Familial Dystonias, Idiopathic,Focal Dystonias,Hereditary Dystonia,Hereditary Dystonias,Idiopathic Familial Dystonia,Idiopathic Familial Dystonias,Primary Dystonia,Primary Dystonias,Pseudodystonias,Psychogenic Dystonia,Psychogenic Dystonias,Secondary Dystonias,Sporadic Dystonia,Sporadic Dystonias,Writer Cramp,Writers Cramp |
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