Yeast cell templated porous hollow silica spheres for rapid hemostasis accompanied by antibacterial action. 2023

Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
State Key Laboratory of Applied Organic Chemistry, Institute of Biochemical Engineering & Environmental Technology, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China. zhaogh@lzu.edu.cn.

Uncontrolled haemorrhage is the leading cause in nearly 91% of pre-hospital deaths, which were considered potentially survivable. In particular, severe trauma is susceptible to infection, which further affects the natural healing process and can even lead to life-threatening sepsis. Therefore, we established Ag@HMSN nanocomposites based on a yeast cell template that combines hemostasis with antibiosis and further studied the effects of different calcination temperatures on the hemostatic and antibacterial properties. From the experimental results, Ag@HMSNs/500 shows excellent bactericidal effect on a mouse skin infection model and outstanding hemostatic effect on a mouse liver injury model, which could be used as the next-generation hemostatic and antibacterial material.

UI MeSH Term Description Entries
D006487 Hemostasis The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION. Hemostases
D006490 Hemostatics Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. Antihemorrhagic,Hemostatic,Antihemorrhagics
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D012441 Saccharomyces cerevisiae A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement. Baker's Yeast,Brewer's Yeast,Candida robusta,S. cerevisiae,Saccharomyces capensis,Saccharomyces italicus,Saccharomyces oviformis,Saccharomyces uvarum var. melibiosus,Yeast, Baker's,Yeast, Brewer's,Baker Yeast,S cerevisiae,Baker's Yeasts,Yeast, Baker
D012822 Silicon Dioxide Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid. Silica,Aerosil,Aerosil 380,Cristobalite,Quso G-32,Quso G32,Tridymite,380, Aerosil,Dioxide, Silicon,G32, Quso,Quso G 32
D016062 Porosity Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance. Porosities
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
April 2021, Materials science & engineering. C, Materials for biological applications,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
December 2021, Molecules (Basel, Switzerland),
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
January 2013, Colloids and surfaces. B, Biointerfaces,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
October 2018, Biomaterials,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
November 2018, Biomaterials science,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
December 2004, Langmuir : the ACS journal of surfaces and colloids,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
May 2006, Journal of colloid and interface science,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
July 2003, Journal of colloid and interface science,
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
July 2011, Advanced materials (Deerfield Beach, Fla.),
Yuting Shi, and Yu Fang, and Xiaoqin Liang, and Congshu Huang, and Yu Liang, and Zheng Yang, and Jianping Yu, and Jianrong Wang, and Guanghui Zhao
March 2014, Langmuir : the ACS journal of surfaces and colloids,
Copied contents to your clipboard!