Cerebral revascularization for complex middle cerebral artery aneurysms: surgical strategies and outcomes in a single center. 2023

Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.

Cerebral revascularization is the ultimate treatment for a subset of complex middle cerebral artery (MCA) aneurysms. The decision for the revascularization strategy should be made during the treatment process. This study aimed to summarize the revascularization strategies for different types of complex MCA aneurysms and their outcomes. The clinical data of patients with complex MCA aneurysms who underwent cerebral revascularization since 2015 were analyzed retrospectively. The aneurysms were classified according to the location and other main characteristics that affect the selection of surgical modalities. The corresponding surgical modalities and treatment outcomes were summarized. A total of 29 patients with 29 complex MCA aneurysms were treated with cerebral revascularization from 2015 to 2022. Treated aneurysms were located at the prebifurcation segment in 7 patients, bifurcation segment in 12 patients, and postbifurcation segment in 10 patients. Surgical modalities in the prebifurcation segment included four high-flow extracranial-to-intracranial (EC-IC) bypasses with aneurysm trapping or proximal occlusion, two IC-IC bypasses with aneurysm excision, and one combination bypass with aneurysm excision. In the bifurcation segment, surgical modalities included two low-flow EC-IC bypasses with aneurysm excision or trapping, six IC-IC bypasses with aneurysm excision, three combination bypasses with aneurysm excision, and one constructive clipping with IC-IC bypass. In the postbifurcation segment, surgical modalities included nine IC-IC bypasses with aneurysm excision and low-flow EC-IC bypass with aneurysm trapping. The revascularization strategy for prebifurcation aneurysms was determined based on the involvement of lenticulostriate arteries, whereas the strategy for bifurcation aneurysms was determined based on the number of distal bifurcations and the shape of the aneurysm. The location of the aneurysm determined the revascularization strategy for aneurysms in the postbifurcation segments. Angiography demonstrated that aneurysms were completely obliterated in 26 cases and shrank in 3 cases, and all bypasses except one were patent. The mean follow-up period was 47.5 months. Three patients developed hemiplegic paralysis, and one developed transient aphasia postoperatively due to cerebral ischemia. No new neurological dysfunction occurred in the other 25 patients with no recurrence or enlargement of aneurysms during the follow-up. Prebifurcation aneurysms involving the lenticulostriate arteries require proximal occlusion with high-flow bypass. Most of the other aneurysms can be safely excised or trapped by appropriate revascularization strategies according to their location and orientation.

UI MeSH Term Description Entries
D002532 Intracranial Aneurysm Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841) Aneurysm, Cerebral,Aneurysm, Intracranial,Basilar Artery Aneurysm,Berry Aneurysm,Brain Aneurysm,Cerebral Aneurysm,Giant Intracranial Aneurysm,Mycotic Aneurysm, Intracranial,Aneurysm, Anterior Cerebral Artery,Aneurysm, Anterior Communicating Artery,Aneurysm, Basilar Artery,Aneurysm, Middle Cerebral Artery,Aneurysm, Posterior Cerebral Artery,Aneurysm, Posterior Communicating Artery,Anterior Cerebral Artery Aneurysm,Anterior Communicating Artery Aneurysm,Middle Cerebral Artery Aneurysm,Posterior Cerebral Artery Aneurysm,Posterior Communicating Artery Aneurysm,Aneurysm, Berry,Aneurysm, Brain,Aneurysm, Giant Intracranial,Aneurysm, Intracranial Mycotic,Aneurysms, Basilar Artery,Aneurysms, Berry,Aneurysms, Brain,Aneurysms, Cerebral,Aneurysms, Giant Intracranial,Aneurysms, Intracranial,Aneurysms, Intracranial Mycotic,Artery Aneurysm, Basilar,Artery Aneurysms, Basilar,Basilar Artery Aneurysms,Berry Aneurysms,Brain Aneurysms,Cerebral Aneurysms,Giant Intracranial Aneurysms,Intracranial Aneurysm, Giant,Intracranial Aneurysms,Intracranial Aneurysms, Giant,Intracranial Mycotic Aneurysm,Intracranial Mycotic Aneurysms,Mycotic Aneurysms, Intracranial
D002548 Cerebral Revascularization Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain. Brain Revascularization,EC-IC Arterial Bypass,Extracranial-Intracranial Arterial Bypass,Microsurgical Revascularization, Cerebral,STA-MCA Bypass,Cerebral Microsurgical Revascularization,Arterial Bypass, EC-IC,Arterial Bypass, Extracranial-Intracranial,Arterial Bypasses, EC-IC,Arterial Bypasses, Extracranial-Intracranial,Bypass, EC-IC Arterial,Bypass, Extracranial-Intracranial Arterial,Bypass, STA-MCA,Bypasses, EC-IC Arterial,Bypasses, Extracranial-Intracranial Arterial,Bypasses, STA-MCA,Cerebral Microsurgical Revascularizations,EC IC Arterial Bypass,EC-IC Arterial Bypasses,Extracranial Intracranial Arterial Bypass,Extracranial-Intracranial Arterial Bypasses,Revascularization, Brain,Revascularization, Cerebral,Revascularization, Cerebral Microsurgical,STA MCA Bypass,STA-MCA Bypasses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D019635 Neurosurgical Procedures Surgery performed on the nervous system or its parts. Procedures, Neurosurgical,Surgical Procedures, Neurologic,Neurologic Surgical Procedure,Neurologic Surgical Procedures,Neurosurgical Procedure,Procedure, Neurologic Surgical,Procedure, Neurosurgical,Procedures, Neurologic Surgical,Surgical Procedure, Neurologic
D020768 Middle Cerebral Artery The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities. Cerebral Artery, Middle,Arteries, Middle Cerebral,Artery, Middle Cerebral,Cerebral Arteries, Middle,Middle Cerebral Arteries

Related Publications

Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
October 2009, Clinical neurology and neurosurgery,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
June 2011, Acta neurochirurgica,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
February 2014, World neurosurgery,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
January 1998, Neurologia medico-chirurgica,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
August 2013, Acta neurochirurgica,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
October 2018, Journal of neurosurgery,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
February 2014, World neurosurgery,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
August 2014, Zhonghua wai ke za zhi [Chinese journal of surgery],
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
September 2017, Journal of neurosurgery,
Xingdong Wang, and Guoqing Han, and Hu Wang, and Yanguo Shang, and Minggang Shi, and Xuan Wang, and Jingang Bao, and Zhiqiang Wang, and Xiaoguang Tong
April 2024, Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences,
Copied contents to your clipboard!