Gut viruses in the pathogenesis of systemic lupus erythematosus.
2023
Hao Li, and
George C Tsokos
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02215, USA. Electronic address: hli13@bidmc.harvard.edu.
UI
MeSH Term
Description
Entries
D008180
Lupus Erythematosus, Systemic
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014780
Viruses
Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.