| D008180 |
Lupus Erythematosus, Systemic |
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. |
Libman-Sacks Disease,Lupus Erythematosus Disseminatus,Systemic Lupus Erythematosus,Disease, Libman-Sacks,Libman Sacks Disease |
|
| D004247 |
DNA |
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). |
DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA |
|
| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
|
| D000974 |
Antibodies, Antinuclear |
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease. |
Anti-DNA Antibodies,Antibodies, Anti-DNA,Antinuclear Antibodies,Antinuclear Autoantibodies,Antinuclear Autoantibody,Antinuclear Factors,Antinuclear Antibody,Antinuclear Factor,Anti DNA Antibodies,Antibody, Antinuclear,Autoantibody, Antinuclear,Factor, Antinuclear |
|
| D001323 |
Autoantibodies |
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them. |
Autoantibody |
|
| D065206 |
Extracellular Traps |
Extracellular structure primarily composed of CHROMATIN and associated PROTEASES. |
Neutrophil Extracellular Traps,EEDTs (Eosinophil Extracellular DNA Traps),Eosinophil Extracellular DNA Traps,Eosinophil Extracellular Traps,Extracellular DNA Traps,NETs (Neutrophil Extracellular Traps),DNA Trap, Extracellular,DNA Traps, Extracellular,EEDT (Eosinophil Extracellular DNA Traps),Eosinophil Extracellular Trap,Extracellular DNA Trap,Extracellular Trap,Extracellular Trap, Eosinophil,Extracellular Trap, Neutrophil,Extracellular Traps, Eosinophil,Extracellular Traps, Neutrophil,NET (Neutrophil Extracellular Traps),Neutrophil Extracellular Trap,Trap, Eosinophil Extracellular,Trap, Extracellular,Trap, Extracellular DNA,Trap, Neutrophil Extracellular,Traps, Eosinophil Extracellular,Traps, Extracellular,Traps, Extracellular DNA,Traps, Neutrophil Extracellular |
|