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We explored the feasibility of using the passive hemagglutination (PHA) test in combination with the hemagglutination inhibition (HI) test for the single-serum diagnosis of rubella. We found by sedimentation analysis of the serum that early 7S antibody produced within 1 month after the onset of the rash had high HI but much lower PHA titers, whereas the PHA titers of antibody produced later were slightly higher than the HI titers. (19S antibody in the early serum had some PHA activity.) This disparity between the HI and PHA activities of the early 7S antibody could be used for the routine diagnosis of rubella. A comparison of the HI titers of the test serum with the PHA titers of mercaptoethanol-treated serum constitutes a simple method for determining whether the serum sample was taken shortly or remotely after the infection.
S Inouye, and
K Satoh, and
T Tajima
January 1987,
Voprosy virusologii,
S Inouye, and
K Satoh, and
T Tajima
June 1970,
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases,
S Inouye, and
K Satoh, and
T Tajima
December 1974,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
S Inouye, and
K Satoh, and
T Tajima
January 1989,
Microbiology and immunology,
S Inouye, and
K Satoh, and
T Tajima
May 1968,
Applied microbiology,
S Inouye, and
K Satoh, and
T Tajima
February 1978,
Infection and immunity,
S Inouye, and
K Satoh, and
T Tajima
January 1975,
Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Bacteriologia, virusologia, parazitologia, epidemiologia,
S Inouye, and
K Satoh, and
T Tajima
August 1969,
Applied microbiology,
S Inouye, and
K Satoh, and
T Tajima
January 1970,
Applied microbiology,
S Inouye, and
K Satoh, and
T Tajima
February 1969,
Minerva medica,
