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A Rare Phenomenon of Lithium-Associated Acne Inversa: A Case Series and Literature Review. 2023

Dhananjay Chaudhari, and Rimsha R Vohra, and Munira Abdefatah Ali, and Huzaifa Nadeem, and Baris Tarimci, and Tulika Garg, and Rawan A Sharari, and Abia Joseph, and Aadil Khan
Department of Psychiatry, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College and Lala Lajpat Rai (LLR) Hospital, Kanpur, IND.

Lithium use has been associated with dermatological issues, including psoriasis, folliculitis, and acneiform outbreaks. The lithium dosage and the therapeutic range of serum lithium levels are closely correlated with the frequency of cutaneous adverse effects. Lithium-induced acne inversa is a less well-known adverse effect, causing significant morbidity. Acne inversa (hidradenitis suppurativa) is a chronic inflammatory illness of the skin seen in the folds of the skin and face and distinguished by the presence of painful nodules and fistulas, as well as a propensity for tissue fibrosis. We report two cases of bipolar affective disorder who received long-term lithium treatment and experienced acne inversa during treatment, which subsided once the lithium was withdrawn.

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