Biomaterial Database

Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis. 1986

R Fitzsimons, and A L Peters

In 20 patients (11 males and nine females, 3 to 65 years old) with fungal keratitis, Fusarium was identified in eight cases, Aspergillus in four, Drechslera in three, and Curvularia, Candida, and Nocardia in one each. In two cases the organism was not identified. Treatment with topical and subconjunctival miconazole along with ketoconazole resulted in healing in 13 cases. Modification of this regimen produced healing in three additional cases. Four cases progressed to blindness despite therapy.

UI	MeSH Term	Description	Entries
D007634	Keratitis	Inflammation of the cornea.	Keratitides
D007654	Ketoconazole	Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.	Nizoral,R-41400,R41,400,R41400,R 41400
D008297	Male		Males
D008825	Miconazole	An imidazole antifungal agent that is used topically and by intravenous infusion.	Brentan,Dactarin,Miconasil Nitrate,Miconazole Nitrate,Monistat,R-14,889,Nitrate, Miconasil,Nitrate, Miconazole,R 14,889,R14,889
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009181	Mycoses	Diseases caused by FUNGI.	Fungus Diseases,Fungal Diseases,Fungal Infections,Fungus Infections,Disease, Fungal,Disease, Fungus,Diseases, Fungal,Diseases, Fungus,Fungal Disease,Fungal Infection,Fungus Disease,Fungus Infection,Infection, Fungal,Infection, Fungus,Infections, Fungal,Infections, Fungus
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths