New approaches and possibilities of studying such categories in general pathology as morphogenesis, pathogenesis and nozology are considered. The study of morphogenesis is shown to be the most perspective in the analysis of functioning of the systems responsible for the specialized function of a given structure; cell regulatory systems (cell cooperations); antagonistic functions at different structural levels. Pathogenesis, as a category of general pathology, can be studied most efficiently by the pathologist when investigating the responsiveness (cell defence systems, neuro-endocrine and local cell regulation, heredity). A role of the pathologist determining nozology is most efficient in the search of etiological, pathogenetic and organospecific (for tumours) markers. The prospects and methodological significance of such investigations are pointed out.