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A monoclonal antibody directed against human apolipoprotein B, which was previously shown in family studies to detect allelic variations (J Biol Chem 1984; 259:6423-6430), has now been identified with the Ag(c) factor. This identification allows the location of the Ag system on the structural gene for apolipoprotein B and on the short arm of human chromosome 2. The epitope corresponding to Ag(c) is located within the amino acid sequence common to apolipoproteins B-100 and B-48. Since a single molecule of apolipoprotein B-100 is present on human LDL, individual LDL possesses either the epitope corresponding to Ag(c) or that corresponding to Ag(g). These studies on allelic variation among human apolipoprotein B species parallel similar studies in animals in which a relationship to atherosclerosis was found.
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
January 2003,
Journal of virology,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
October 1987,
Scandinavian journal of immunology,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
September 1987,
Journal of immunological methods,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
July 2009,
Molecular immunology,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
February 1987,
American heart journal,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
February 1994,
FEBS letters,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
November 2006,
Chembiochem : a European journal of chemical biology,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
August 1982,
Human immunology,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
June 1986,
FEBS letters,
M T Robinson, and
V N Schumaker, and
R Butler, and
K Berg, and
L K Curtiss
May 2015,
Journal of immunological methods,
