BIOMAT Database Logo BIOMAT Database Logo

Studies on positive inotropic agents. II. Synthesis of (4-substituted 1-piperazinylcarbonyl)-2-(1H)-quinolinone derivatives. 1986

M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa

UI MeSH Term Description Entries
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D010879 Piperazines Compounds that are derived from PIPERAZINE.
D011804 Quinolines
D002316 Cardiotonic Agents Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). Cardiac Stimulant,Cardiac Stimulants,Cardioprotective Agent,Cardioprotective Agents,Cardiotonic,Cardiotonic Agent,Cardiotonic Drug,Inotropic Agents, Positive Cardiac,Myocardial Stimulant,Myocardial Stimulants,Cardiotonic Drugs,Cardiotonics,Agent, Cardioprotective,Agent, Cardiotonic,Drug, Cardiotonic,Stimulant, Cardiac,Stimulant, Myocardial
D002621 Chemistry A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D055598 Chemical Phenomena The composition, structure, conformation, and properties of atoms and molecules, and their reaction and interaction processes. Chemical Concepts,Chemical Processes,Physical Chemistry Concepts,Physical Chemistry Processes,Physicochemical Concepts,Physicochemical Phenomena,Physicochemical Processes,Chemical Phenomenon,Chemical Process,Physical Chemistry Phenomena,Physical Chemistry Process,Physicochemical Phenomenon,Physicochemical Process,Chemical Concept,Chemistry Process, Physical,Chemistry Processes, Physical,Concept, Chemical,Concept, Physical Chemistry,Concept, Physicochemical,Concepts, Chemical,Concepts, Physical Chemistry,Concepts, Physicochemical,Phenomena, Chemical,Phenomena, Physical Chemistry,Phenomena, Physicochemical,Phenomenon, Chemical,Phenomenon, Physicochemical,Physical Chemistry Concept,Physicochemical Concept,Process, Chemical,Process, Physical Chemistry,Process, Physicochemical,Processes, Chemical,Processes, Physical Chemistry,Processes, Physicochemical
D066298 In Vitro Techniques Methods to study reactions or processes taking place in an artificial environment outside the living organism. In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In

Related Publications

M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on 2(1H)-quinolinone derivatives as neuroleptic agents I. Synthesis and biological activities of (4-phenyl-1-piperazinyl)-propoxy-2(1H)-quinolinone derivatives.
November 1988, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Novel positive inotropic agents: synthesis and biological activities of 6-(3-amino-2-hydroxypropoxy)-2(1H)-quinolinone derivatives.
October 1992, Journal of medicinal chemistry,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on positive inotropic agents. VI. Synthesis of 1-aromatic ring substituted 4-(3,4-dimethoxybenzoyl)piperazine derivatives.
July 1988, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on positive inotropic agents. V. Synthesis of 1-heteroaroylpiperazine derivatives.
June 1988, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activities of optically active alpha-amino acid derivatives of 2(1H)-quinolinone and oxindole.
February 1987, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activity of the metabolites of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid.
November 1986, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. 2-(4-Chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propi oni c acid and related compounds.
September 1985, Chemical & pharmaceutical bulletin,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Compounds with positive inotropic activity, III: Synthesis of 4-aminoquinoline derivatives as potential positive inotropic agents.
September 1990, Archiv der Pharmazie,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
[Studies on diphenylmethane derivatives. II. Synthesis of N-substituted-1-(3,4-dimethoxyphenyl)-1-(2,3- or 4-substituted phenyl)methylamine derivatives].
January 1975, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Tominaga, and E Yo, and H Ogawa, and S Yamashita, and Y Yabuuchi, and K Nakagawa
Studies on cardiotonic agents. III. Synthesis of 1-[1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]-3-substituted 2-imidazolidinone and 2-imidazolidinethione derivatives.
September 1990, Chemical & pharmaceutical bulletin,
Copied contents to your clipboard!