Antimony (Sb) and arsenic (As) co-contamination occurs in Sb smelting areas and is harmful to the surrounding ecological environment. The purpose of this study is to explore the spatial distribution characteristics of Sb and As in abandoned Sb smelting area and carry out risk assessments. Soil samples were collected from the smelting area profile and background points, and groundwater samples were also collected. Samples from two geological background sections were collected to understand the geological background characteristics of Sb and As. The spatial distribution was drawn via the inverse distance weighted interpolation method. The hazard assessment was carried out by the geo-accumulation index and potential ecological hazard methods. The results showed that special high geological background value of Sb and As in study area. Sb and As co-contamination is one of the characters in soil. And the contents of Sb and As decrease as depth increases, reflecting the weak migration capacity. The spatial distribution of Sb and As is affected by slag distribution and rainfall leaching. The Sb content in groundwater was higher in the wet and normal seasons than in the dry season, slag leaching may be one of the elements. The potential ecological hazards of Sb and As are high and considerable, respectively. In abandoned smelting area with high geological background values, it is necessary to focus on the pollution abatement and protection of ecological health.