-transparent.png){kind=logo}
Synthesis of diarylmethyl thioethers via a DABCO-catalyzed 1,6-conjugate addition reaction of p-quinone methides with organosulfur reagents. 2023
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com.
A rapid and simple method was developed for the synthesis of diarylmethyl thioethers via a DABCO-catalyzed 1,6-conjugate addition reaction of para-quinone methides (p-QMs) with organosulfur reagents. A series of diarylmethyl thioethers were synthesized at 13-85% yields by this method. After that, the antibacterial activities of synthesized diarylmethyl thioethers and their derivatives were evaluated. The MIC range (μg mL-1) against Staphylococcus aureus ATCC 25923 and clinically isolated methicillin-resistant S. aureus was 8-128 and 64-128, respectively.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
March 2022,
The Journal of organic chemistry,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
June 2018,
Organic & biomolecular chemistry,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
October 2018,
ACS omega,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
December 2021,
The Journal of organic chemistry,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
February 2018,
ACS omega,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
October 2021,
Molecules (Basel, Switzerland),
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
May 2018,
Organic letters,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
February 2016,
Organic letters,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
September 2022,
Organic letters,
Ming-Shan Shuai, and
Xiang Guan, and
Xing-Hai Fei, and
Mao Zhang, and
Xiao-Zhong Fu, and
Bin He, and
Yong-Long Zhao
January 2016,
Angewandte Chemie (International ed. in English),
