Effects of paradoxical sleep deprivation in the rabbit. 1986

R T Pivik, and F W Bylsma, and P Cooper

The effects of nonpharmacologically-induced deprivation of paradoxical sleep for a 24 hour period were studied in rabbits. Response characteristics commonly associated with the deprivation procedure in other species were observed, as well as features apparently peculiar to the rabbit. Like other mammals, rabbits: (1) show increased attempts to experience PS during the deprivation procedure relative to the baseline occurrence of PS; (2) become increasingly difficult to arouse from PS as the deprivation period progresses; (3) show increased amounts of PS (rebound) in post-deprivation recordings relative to baseline; and (4) compensate for only one-third of the PS deficit incurred during deprivation. Rabbits' response to PS deprivation differs from other mammals in the following ways: (1) the deprivation procedure is truly selective, significantly affecting only amounts of PS and not total sleep time or other sleep stages; (2) the rebound response is restricted to the light phase of the light-dark cycle on the first recovery day; and (3) as indexed by eye movement density, phasic activity during PS is not enhanced during the recovery period. Given that the crucial factor in the PS deprivation-compensation phenomenon is thought to be the deprivation and subsequent enhanced occurrence of phasic events, and considering that events within the oculomotor system have been emphasized in this regard, the results of this investigation suggest the existence of species differences regarding the nature and form of the compensatory response to PS deprivation.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D003624 Darkness The absence of light. Darknesses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012892 Sleep Deprivation The state of being deprived of sleep under experimental conditions, due to life events, or from a wide variety of pathophysiologic causes such as medication effect, chronic illness, psychiatric illness, or sleep disorder. Inadequate Sleep,Insufficient Sleep,Insufficient Sleep Syndrome,REM Sleep Deprivation,Sleep Debt,Sleep Fragmentation,Sleep Insufficiency,Deprivation, REM Sleep,Deprivation, Sleep,Fragmentation, Sleep,Insufficiencies, Sleep,Insufficiency, Sleep,Insufficient Sleep Syndromes,Sleep Deprivation, REM,Sleep Insufficiencies,Sleep, Inadequate,Sleep, Insufficient,Syndrome, Insufficient Sleep
D012895 Sleep, REM A stage of sleep characterized by rapid movements of the eye and low voltage fast pattern EEG. It is usually associated with dreaming. Fast-Wave Sleep,Paradoxical Sleep,Rapid Eye Movements,Rhombencephalic Sleep,Sleep, Fast-Wave,REM Sleep,Eye Movement, Rapid,Eye Movements, Rapid,Fast Wave Sleep,Movement, Rapid Eye,Movements, Rapid Eye,Rapid Eye Movement,Sleep, Fast Wave,Sleep, Paradoxical,Sleep, Rhombencephalic
D014851 Wakefulness A state in which there is an enhanced potential for sensitivity and an efficient responsiveness to external stimuli. Wakefulnesses

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