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A survey of 300 patients with burns covering more than 30 per cent of the body surface area indicated that 33 patients had proven wound infection with anaerobic bacteria and 11 patients showed positive blood cultures. Although metronidazole was the anti-bacterial agent of choice for treating these 33 patients, treatment was not always successful since 7 patients died. The most common sites of infection were the perineum and upper parts of the legs.
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