Neurocysticercosis and hydrocephalus: the value of ventriculoperitoneal shunting in its management. 2023

Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
Research Unit on Neuroinflammation, Departamento de Medicina Genomica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas - Universidad Nacional Autónoma de México/Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, Tlalpan, 14269, México City, México.

Hydrocephalus is the main complication of extraparenchymal neurocysticercosis (EP-NC). Its symptomatic management relies mainly on the placement of a ventriculoperitoneal shunt (VPS). Previous studies have shown that this surgical procedure is associated with a poor prognosis, but current information is lacking. We included 108 patients with a definitive diagnosis of EP-NC and hydrocephalus requiring VPS placement. We evaluated their demographic, clinical, and inflammatory characteristics, as well as the frequency of complications related to VPS placement. Hydrocephalus was present at the time of NC diagnosis in 79.6% of patients. VPS dysfunction occurred in 48 patients (44.4%), mainly within the first year after placement (66.7%). The dysfunctions were not associated with the location of the cyst, the inflammatory characteristics of the cerebrospinal fluid or the administration of cysticidal treatment. They were significantly more frequent in patients in whom the decision to place a VPS was made in the emergency department. Two years after VPS, patients' Karnofsky score averaged 84.6±15 and only one patient died of a cause directly related to VPS. This study confirmed the utility of VPS and showed a significant improvement in the prognosis of patients requiring VPS compared with previous studies.

UI MeSH Term Description Entries
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006849 Hydrocephalus Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA. Communicating Hydrocephalus,Congenital Hydrocephalus,Obstructive Hydrocephalus,Post-Traumatic Hydrocephalus,Aqueductal Stenosis,Cerebral Ventriculomegaly,Fetal Cerebral Ventriculomegaly,Hydrocephalus Ex-Vacuo,Hydrocephaly,Aqueductal Stenoses,Cerebral Ventriculomegalies,Cerebral Ventriculomegalies, Fetal,Cerebral Ventriculomegaly, Fetal,Fetal Cerebral Ventriculomegalies,Hydrocephalus Ex Vacuo,Hydrocephalus Ex-Vacuos,Hydrocephalus, Communicating,Hydrocephalus, Congenital,Hydrocephalus, Obstructive,Hydrocephalus, Post-Traumatic,Post Traumatic Hydrocephalus,Stenoses, Aqueductal,Stenosis, Aqueductal,Ventriculomegalies, Cerebral,Ventriculomegalies, Fetal Cerebral,Ventriculomegaly, Cerebral,Ventriculomegaly, Fetal Cerebral
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D017287 Ventriculoperitoneal Shunt Surgical creation of a communication between a cerebral ventricle and the peritoneum by means of a plastic tube to permit drainage of cerebrospinal fluid for relief of hydrocephalus. (From Dorland, 28th ed) Ventriculo-peritoneal Shunt,Shunt, Ventriculo-peritoneal,Shunt, Ventriculoperitoneal,Shunts, Ventriculo-peritoneal,Shunts, Ventriculoperitoneal,Ventriculo peritoneal Shunt,Ventriculo-peritoneal Shunts,Ventriculoperitoneal Shunts
D020019 Neurocysticercosis Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50) CNS Cysticercosis,Central Nervous System Cysticercosis,Cerebral Coenurosis,Cerebral Cysticercosis,Cysticercosis, Brain,Cysticercosis, Central Nervous System,Neurocoenurosis,Brain Cysticercosis,CNS Cysticercoses,Cerebral Coenuroses,Cerebral Cysticercoses,Coenurosis, Cerebral,Cysticercosis, CNS,Cysticercosis, Cerebral,Neurocoenuroses,Neurocysticercoses

Related Publications

Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
May 1973, British medical journal,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
December 1984, AORN journal,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
May 1998, Archives of neurology,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
October 1996, Archives of ophthalmology (Chicago, Ill. : 1960),
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
June 2011, Veterinary surgery : VS,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
September 1997, Neurologia medico-chirurgica,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
January 1979, Acta neurochirurgica. Supplementum,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
March 1962, Journal of the Indian Medical Association,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
January 2021, Frontiers in neuroscience,
Lya Cruz, and Edgar Pacheco, and Walter Soto, and Roberto Cong, and Roberto Suastegui, and Sergio Moreno-Jimenez, and Agnès Fleury
January 2018, Pakistan journal of medical sciences,
Copied contents to your clipboard!