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We have devised a computer-assisted method for objective estimation of liver mass from the right lateral projection of radiocolloid images of the liver. Gamma-camera images were digitized, preprocessed, and stored in computer memory. The definition of liver for area measurement was adaptively determined by means of a Laplacian operator that measures change in radioactivity slope associated with the liver margin. Individual thresholds were calculated for each of 16 subregions. A liver-mass index was derived from a linear regression model correlating the area of the right lateral projection with liver weight at autopsy in 50 patients whose livers weighed between 0.8 to 3.0 Kg. The correlation coefficient found for this method was 0.83 using the equation: Liver Mass [kg] = Area [cm2]/275 [kg/cm2]--0.215 [kg]. Liver-mass estimates using an alternative computer-assisted method or representative manual methods adapted for gamma-camera images showed lower correlation with liver weight at autopsy.
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
April 1982,
Computer programs in biomedicine,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
September 1997,
Nuclear medicine communications,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
April 1975,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
February 1979,
The British journal of radiology,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
January 1992,
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
October 1971,
Computers and biomedical research, an international journal,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
October 2005,
Pharmaceutical research,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
January 2004,
Revista espanola de medicina nuclear,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
November 1977,
Medical & biological engineering & computing,
E A Eikman, and
G A Mack, and
V K Jain, and
J A Madden
January 1977,
La Ricerca in clinica e in laboratorio,
