[Acetylsalicylic acid in primary and secondary prevention of atherosclerotic cardiovascular disease]. 2023

O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
Research Institute of Health Organization and Medical Management, Moscow, Russia.

The article is devoted to an urgent problem - primary and secondary prevention of atherosclerotic cardiovascular diseases. Modern approaches to management tactics depending on age and the appointment of antiplatelet therapy with acetylsalicylic acid in low doses from 75 to 150 mg/day are presented. At the same time, the relatively high effectiveness of the use of ASA for primary prevention in men 40-69 years old without an increased risk of bleeding from the gastrointestinal tract is shown. Low doses of ASA provide little benefit in reducing the risk of CVD in people 40 years and older, when there is no history of CVD, but at the same time they are at increased risk of CVD.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002318 Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. Adverse Cardiac Event,Cardiac Events,Major Adverse Cardiac Events,Adverse Cardiac Events,Cardiac Event,Cardiac Event, Adverse,Cardiac Events, Adverse,Cardiovascular Disease,Disease, Cardiovascular,Event, Cardiac
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D001241 Aspirin The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) Acetylsalicylic Acid,2-(Acetyloxy)benzoic Acid,Acetysal,Acylpyrin,Aloxiprimum,Colfarit,Dispril,Easprin,Ecotrin,Endosprin,Magnecyl,Micristin,Polopirin,Polopiryna,Solprin,Solupsan,Zorprin,Acid, Acetylsalicylic
D041981 Gastrointestinal Tract Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS). Digestive Tract,GI Tract,Digestive Tracts,GI Tracts,Gastrointestinal Tracts
D050197 Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. Atherogenesis,Atherogeneses,Atheroscleroses
D055502 Secondary Prevention The prevention of recurrences or exacerbations of a disease or complications of its therapy. Disease Prevention, Secondary,Early Therapy,Relapse Prevention,Secondary Disease Prevention,Disease Preventions, Secondary,Early Therapies,Prevention, Relapse,Prevention, Secondary,Prevention, Secondary Disease,Preventions, Relapse,Preventions, Secondary,Preventions, Secondary Disease,Relapse Preventions,Secondary Disease Preventions,Secondary Preventions,Therapies, Early,Therapy, Early

Related Publications

O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
January 2022, Vnitrni lekarstvi,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
October 2010, Der Internist,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
June 2001, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
May 2019, European journal of preventive cardiology,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
July 2019, Canadian family physician Medecin de famille canadien,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
December 2005, Deutsche medizinische Wochenschrift (1946),
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
July 2004, Nederlands tijdschrift voor geneeskunde,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
April 2005, Nederlands tijdschrift voor geneeskunde,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
September 2022, Cleveland Clinic journal of medicine,
O Sh Oynotkinova, and S T Matskeplishvili, and O M Maslennikova, and A I Pavlov, and A G Poberezhskaya
October 2004, Nederlands tijdschrift voor geneeskunde,
Copied contents to your clipboard!