Selection for postweaning gain in rats: I. Correlated response in feed utilization and body composition. 1986

J G Rios, and M K Nielsen, and G E Dickerson, and J A DeShazer

Response to selection for up (U) and (D) 3- to 9-wk gain in rats on average daily gain (ADG), average daily feed intake (ADI), gain/feed (G/F), body composition (BC), fasting metabolic rate per unit metabolic size (MR) and partial efficiency of weight gain (ADG/Fg) was evaluated after 34 generations of mass selection. At 3-wk weaning, 120 litters representing F1 crosses of two replicates within each of the U, D and control (C) selection lines were divided within sexes between bulk-feeder and tube-feeder cage types for recording feed intake until 9 wk of age. Rats from tube-feeder cages representing 16 litters/line were utilized for MR and BC data. Response in ADG was asymmetrical; 16% higher for U line but only 8% lower in D line, compared with C line. Correlated responses were positive and significant in both U and D lines for ADI (6% and -3%) and G/F (5% and -5%). Line differences in MR were not significant but both selected lines were slightly higher than C line in MR at 6 wk of age, and the reverse at 9 wk of age. Over the period of 6 to 9 wk of age, maintenance requirements per unit metabolic size and ADG/Fg were 1 and 5% above for the U and -1 and -4% for D lines, relative to C line. Females of both selected lines were fatter than C line (P less than .05) at 9 wk of age, but only D line males were fatter than C line.

UI MeSH Term Description Entries
D008297 Male Males
D001823 Body Composition The relative amounts of various components in the body, such as percentage of body fat. Body Compositions,Composition, Body,Compositions, Body
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D005260 Female Females
D006128 Growth Gradual increase in the number, the size, and the complexity of cells of an individual. Growth generally results in increase in ORGAN WEIGHT; BODY WEIGHT; and BODY HEIGHT.
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000824 Animal Nutritional Physiological Phenomena Nutritional physiology of animals. Animal Nutrition Physiology,Animal Nutritional Physiology Phenomena,Animal Nutritional Physiological Phenomenon,Animal Nutritional Physiology,Animal Nutritional Physiology Phenomenon,Veterinary Nutritional Physiology,Nutrition Physiologies, Animal,Nutrition Physiology, Animal,Nutritional Physiology, Animal,Nutritional Physiology, Veterinary,Physiology, Animal Nutrition,Physiology, Animal Nutritional,Physiology, Veterinary Nutritional
D012641 Selection, Genetic Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population. Natural Selection,Genetic Selection,Selection, Natural
D014886 Weaning Permanent deprivation of breast milk and commencement of nourishment with other food. (From Stedman, 25th ed) Weanings
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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