Biomaterial Database

Velocity and asymmetry of optokinetic nystagmus in the evaluation of vestibular lesions. 1986

M Magnusson, and I Pyykkö

Optokinetic nystagmus (OKN) at a constant stimulus velocity of 90 degrees/s was studied in 50 healthy subjects and three different groups of patients: 10 with vestibular neuritis (VN), 17 with unilateral infratentorial lesion (UI) and 13 patients with bilateral infratentorial lesion (BI). Among healthy subjects, OKN decreased with age in those over 42 and 44 years for maximum and mean velocity, respectively. The maximum velocity of OKN discriminated between the healthy subjects and the groups of patients rather better than did mean velocity of OKN. Asymmetry of either mean or maximum velocity contributed only marginally to correct group assignment. By subjecting test data on velocity and asymmetry variables to linear discriminant function analysis, 80% of subjects could be correctly classified as healthy/not healthy, and 64% assigned to the correct group according to diagnosis. Analysis of OKN data satisfactorily discriminated BI and UI patients from VN patients and healthy subjects, and is thus useful in assessing infratentorial vestibular lesions.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009443	Neuritis	A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.	Polyneuritis,Neuritis, Motor,Neuritis, Peripheral,Neuritis, Sensory,Motor Neuritides,Motor Neuritis,Neuritides,Neuritides, Motor,Neuritides, Peripheral,Neuritides, Sensory,Peripheral Neuritides,Peripheral Neuritis,Polyneuritides,Sensory Neuritides,Sensory Neuritis
D009760	Nystagmus, Physiologic	Involuntary rhythmical movements of the eyes in the normal person. These can be naturally occurring as in end-position (end-point, end-stage, or deviational) nystagmus or induced by the optokinetic drum (NYSTAGMUS, OPTOKINETIC), caloric test, or a rotating chair.	Nystagmus, Barany,Nystagmus, Caloric,Nystagmus, End-Position,Nystagmus, Positional,Nystagmus, Post-Rotatory,Nystagmus, Thermal,Nystagmus, Barany's,Nystagmus, Physiological,Physiologic Nystagmus,Barany Nystagmus,Barany's Nystagmus,Caloric Nystagmus,End-Position Nystagmus,Nystagmus, Baranys,Nystagmus, End Position,Nystagmus, Post Rotatory,Physiological Nystagmus,Positional Nystagmus,Post-Rotatory Nystagmus,Thermal Nystagmus
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D012044	Regression Analysis	Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.	Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D004585	Electrooculography	Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.	EOG,Electrooculograms,Electrooculogram
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000160	Vestibulocochlear Nerve Diseases	Pathological processes of the VESTIBULOCOCHLEAR NERVE, including the branches of COCHLEAR NERVE and VESTIBULAR NERVE. Common examples are VESTIBULAR NEURITIS, cochlear neuritis, and ACOUSTIC NEUROMA. Clinical signs are varying degree of HEARING LOSS; VERTIGO; and TINNITUS.	Acoustic Nerve Diseases,Cochlear Nerve Diseases,Cranial Nerve VIII Diseases,Vestibular Nerve Diseases,Acoustic Nerve Disorders,Cochlear Nerve Disorders,Cochlear Neuritis,Cranial Nerve VIII Disorders,Eighth Cranial Nerve Diseases,Vestibular Nerve Disorders,Acoustic Nerve Disease,Acoustic Nerve Disorder,Cochlear Nerve Disease,Cochlear Nerve Disorder,Cochlear Neuritides,Neuritides, Cochlear,Neuritis, Cochlear,Vestibular Nerve Disease,Vestibular Nerve Disorder,Vestibulocochlear Nerve Disease
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults